De novo synthesis and lectin binding studies of unsaturated carba-pyranoses.

نویسندگان

  • Timo Leermann
  • Oliver Block
  • Michael A L Podeschwa
  • Uwe Pfüller
  • Hans-Josef Altenbach
چکیده

Starting from branched para-benzoquinones a practical and highly flexible route is described for the preparation of unsaturated carbapyranoses. The potential of the synthesized galactose analogues to act as competitive inhibitors in lectin-carbohydrate interactions is investigated by means of Surface Plasmon Resonance (SPR) Spectroscopy.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 8 17  شماره 

صفحات  -

تاریخ انتشار 2010